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Marcus Munafò PhD

Reader in Biological Psychology

Contact Details

Telephone: +44.117.9546841
Fax: +44.117.9288588
Email: Marcus.Munafo@bris.ac.uk

Room 5D5

Personal Website

Biographical details

Reader in Biological Psychology, Department of Experimental Psychology
University of Bristol (2007-present)

Lecturer, Department of Experimental Psychology
University of Bristol (2005-2007)

Visiting Professor, Department of Psychiatry
University of Pennsylvania (2004-2005)

Research Fellow, Department of Clinical Pharmacology
University of Oxford (1999-2005)


Research interests

My interests are in the role of molecular genetic influences on addictive behaviour and the use of social drugs (primarily nicotine and alcohol), in particular the behavioural, cognitive and neural mechanisms that mediate these relationships. Candidate genes associated with dopaminergic and serotonergic neurotransmission are of particular interest, as these have been shown to be related to addictive behaviour, and may influence the development of learning pathways implicated in addiction in psychological models of addiction.


Recent and current grants

Munafò, M.R. (P.I.) Effects of CO2 Challenge on Stress Response in Smokers. National Alliance for Research on Schizophrenia and Depression (2007-2009).

Munafò, M.R. (P.I.) Using Genotype to Tailor Prescribing of Nicotine Replacement Therapy: A Randomised Controlled Trial Assessing Impact upon Adherence. National Health Service, (2007-2008).

Munafò, M.R. (P.I.), Penton-Voak, I.S., Benton, C.P. Are you Looking at Me II? Effects of Alcohol Consumption of Processing of Perceptual Cues of Emotional Expression. Alcohol Education and Research Council, (2007-2008).

Gregg, P.A. (P.I.), Burgess, S., Lawlor, D.A., Propper, C., Windmeijer, F., Davey-Smith, G., Steele, F.A., Sterne, J., Ness, A.R., Feinstein, L., Lewis, G., Munafò, M.R. An Examination of the Impact of Family Socio-Economic Status on Outcomes in Late Childhood and Adolescence. Economic and Social Research Council, (2006-2011).

Rowe, A.C. (P.I.), Munafò, M.R. Attentional Bias Training and Attachment Anxiety in Adults. British Academy (2006-2007).

Munafò, M.R. (P.I.), Penton-Voak, I.S., Benton, C.P. Are you Looking at Me? Effects of Alcohol Consumption of Processing of Perceptual Cues of Emotional Expression. Alcohol Education and Research Council, (2005-2006).

Munafò, M.R. (P.I.), Mackintosh, B., MacLeod, C. Attentional Bias Training in Social Drinkers. Alcohol Education and Research Council, (2005-2006).

Collaborations

Dr Anne Lingford-Hughes and Dr John Potokar
Academic Unit of Psychiatry, University of Bristol

Dr Elaine Johnstone and Dr Paul Aveyard
Department of Clinical Pharmacology, University of Oxford

Professor Jonathan Flint
Wellcome Trust Centre for Human Genetics, University of Oxford

Dr Bundy Mackintosh
MRC Cognition and Brain Sciences Unit, Cambridge

Professor Theresa Marteau
Psychology and Genetics Research Group, Kings College London

Dr Caryn Lerman
Department of Psychiatry, University of Pennsylvania

Dr Brian Hitsman
Department of Psychiatry and Human Behavior, Brown University


Consulting

European Commision
Working Group on Smokeless Tobacco Products

American Institutes for Research
Surgeon General’s Report


Current PhD students

Luca Saraceno:
“Genetic and environmental risk factors for substance use” (University of Cardiff)

Alia Ataya:
“Cognitive and biobehavioural mechanisms of alcohol use”

Sally Adams:
“Neurobiological determinants of alcohol use”

Emma Mullings:
“Cognitive and biobehavioural mechanisms of nicotine addiction”

Robin Carhart-Harris:
“Effects of ecstasy on sleep and sleep disturbance”

Marietta Papadatou-Pastou:
"Lateralization and handedness in humans" (University of Oxford)



Some recent publications

A full list of publications is available here.

http://marcus-munafo.psy.bris.ac.uk/Publications/index.html

David, S.P., Strong, D.R., Munafò, M.R., Brown, R.A., Lloyd-Richardson, E.E., Wileyto, E.P., Evins, A.E., Shields, P.G., Lerman C. & Niaura, R. (2007). Bupropion efficacy for smoking cessation is influenced by the DRD2 Taq1A polymorphism: Analysis of pooled data from two clinical trials. Nicotine and Tobacco Research, 9, 1251-1257.

Lerman, C., Schnoll, R.A. & Munafò, M.R. (2007). Genetics and smoking cessation: Improving outcome in patients at risk. American Journal of Preventive Medicine, 33, S398-S405.

David, S.P., Munafò, M.R., Johansen-Berg, H., Sweet, L., Cohen, R. Niaura, R., Rogers, R.D., Matthews, P.M. & Walton, R.T. (2007). Effects of nicotine abstinence on cue-elicited ventral striatum/nucleus accumbens activation in female cigarette smokers: A functional magnetic resonance imaging study. Brain Imaging and Behavior, 1, 43-57.

Collins, B.N., Wileyto, E.P., Murphy, M.F.G. & Munafò, M.R. (2007). Adolescent environmental tobacco smoke exposure, not prenatal exposure to tobacco, predicts adolescent academic achievement failure. Journal of Adolescent Health, 41, 363-370.

Munafò, M.R., Mannie, Z.N., Cowen, P.J., Harmer, C.J. & McTavish, S.B. (2007). Effects of acute tyrosine depletion on subjective craving and selective processing of smoking-related cues in abstinent cigarette smokers. Journal of Psychopharmacology, 192, 317-324.

David, S.P., Brown, R.A., Papandonatos, G.D., Kahler, C., Lloyd-Richardson, E.E., Munafò, M.R., Shields, P.G., Lerman, C., Strong, D., McCaffery, J. & Niaura, R. (2007). Pharmacogenetic clinical trial of sustained-release bupropion for smoking cessation. Nicotine and Tobacco Research, 9, 821-833.

Rigotti, N., Munafò, M.R., Stead, L. & Murphy, M.F.G. (2007). Interventions for smoking cessation in hospitalised patients. Cochrane Library, Issue 3. Oxford: Update Software.

Johnstone, E.C., Elliot, K.M., David, S.P., Murphy, M.F.G., Walton, R.T. & Munafò, M.R. (2007). Association of COMT Val108/158Met genotype with smoking cessation in a nicotine replacement therapy randomized trial. Cancer Epidemiology Biomarkers and Prevention, 16, 1065-1069.

Aveyard, P., Brown, K., Saunders, C., Alexander, A., Johnstone, E.C., Munafò, M.R. & Murphy, M.F.G. (2007). A pragmatic randomised controlled trial to examine the effectiveness of additional behavioural support in stopping smoking in primary care - the PIP trial (ISRCTN 05689186). Thorax, 62, 898-903.

Hitsman, B., Spring, B., Pingitore, R., Munafò, M.R. & Hedeker, D. (2007). Effects of acute tryptophan depletion on the attentional salience of smoking cues. Psychopharmacology (Berl.), 192, 317-324.

Munafò, M.R., Johnstone, E.C. (2007). Effects of dopamine D2 receptor gene polymorphisms on smoking cessation: abstinence and withdrawal symptoms. Pharmacogenomics, 8, 513-517.

Munafò, M.R., Matheson, I.J. & Flint, J. (2007). Association of the DRD2 Taq1 polymorphism and alcoholism: A meta-analysis of case-control studies and evidence of publication bias. Molecular Psychiatry, 12, 454-461.

Munafò, M.R., Zetteler, J.I. & Clark, T.G. (2007). Personality and smoking status: A meta-analysis. Nicotine and Tobacco Research, 9, 405-413.

Munafò, M.R. & Black, S. (2007). Personality and smoking status: A longitudinal analysis. Nicotine and Tobacco Research, 9, 397-404.

David, S.P., Munafò, M.R., Murphy, M.F.G., Walton, R.T. & Johnstone, E.C. (2007). The serotonin transporter 5-HTTLPR polymorphism and treatment response to nicotine patch: Follow-up of a randomized controlled trial. Nicotine and Tobacco Research, 9, 225-231.

Munafò, M.R., Elliot, K.M., Murphy, M.F.G., Walton, R.T. & Johnstone, E.C. (2007). Association of the mu-opioid receptor gene with smoking cessation. The Pharmacogenomics Journal, 7, 353-361.

Flint, J. & Munafò, M.R. (2007). The endophenotype concept in psychiatric genetics. Psychological Medicine, 37, 163-180.

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